Int. Adv. Otol. 2011; 7(1) 96-101

Could Bone Cement Cause Ototoxicity?
Orhan Kemal Kahveci, Ahmet Cangal, Murat Cem Miman, Erdoğan Okur, Ali Altuntas. 
Afyon Kocatepe University, Faculty of Medicine, Department of Otolaryngology,  Afyon, Turkey. orhangs75@hotmail.com

Objective: The aim of the study was to find out the possible ototoxic effect of glass ionomer bone cement. 

Materials and Methods: In the study, twenty ears of the ten New Zealand white rabbits were used. The left ears of the rabbits were used as study group and injected intratympanically only 0.1 gram glass powder component of the bone cement which solved in isotonic solution. The right ears of the rabbits were used as control group and injected intratympanically only isotonic solution. Cochlear functions were measured before and after injections with distortion product otoacustic emission (DPOAE) testing.

Results: The first day after intratympanic injections, the DPOAE amplitudes of the left ears were worse than right ears. After one week and one month there was no significant difference between right and left ears.

Conclusion: Our study supports that glass powder component of the bone cement is not ototoxic.