The Journal of International
Advanced Otology
Original Article

A Pilot Study Using Intratympanic Methylprednisolone for Treatment of Persistent Posterior Canal Benign Paroxysmal Positional Vertigo


Department of Otorhinolaryngology, Hospital de Cabueñes, Gijón, Spain


Department of Otorhinolaryngology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain


Department of Otorhinolaryngology, Hospital Costa del Sol, Marbella, Spain


Department of Genomic Medicine, GENYO - for Genomics and Oncological Research- Pfizer/University of Granada, Otology and Neurotology Gropu, Granada, Spain

J Int Adv Otol 2016; 12: 321-325
DOI: 10.5152/iao.2016.3014
Read: 2242 Downloads: 968 Published: 03 September 2019


OBJECTIVE: To assess the effect of intratympanic methylprednisolone (ITMP) in posterior canal benign paroxysmal positional vertigo (BPPV) that fails treatment involving repositioning maneuver in a case series.


MATERIALS and METHODS: Nine patients with persistent posterior canal BPPV after 6 or more repositioning maneuvers were treated by ITMP (two weekly doses of 0.3–0.4 mL at 40 mg/mL) before repeating the repositioning procedures.


RESULTS: Following ITMP treatment, 7 out of 9 patients were relieved of their symptoms and did not exhibit positional nystagmus after 1 or 2 repositioning maneuvers. The number of positional maneuvers performed before and after ITMP treatment in these 7 patients showed a statistically significant (p=0.016) reduction in the amount of repositioning treatments required. None of the 7 respondent patients showed any relapses during the follow-up period (follow-up range: 11–95 months).


CONCLUSION: Administering ITMP before resuming repositioning procedures can be a useful treatment for persistent BPPV of the posterior canal.

EISSN 2148-3817