The Journal of International
Advanced Otology
Original Article

Electrophysiological Changes Associated with the Progression of Noise-Induced Hearing Loss

1.

Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea

2.

Department of Otorhinolaryngology-Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University, Seoul, Republic of Korea 3

3.

Department of Computer Science and Engineering, Korea University College of Informatics, Seoul, Republic of Korea

4.

Jenks Vestibular Physiology Lab, Massachusetts Eye and Ear Infirmary, Massachusetts, USA

J Int Adv Otol 2023; 19: 485-491
DOI: 10.5152/iao.2023.231192
Read: 609 Downloads: 215 Published: 30 November 2023

BACKGROUND: The aim of this study is to evaluate the clinical characteristics and electrophysiological changes in patients with different degrees of noise-induced hearing loss compared with those of normal controls to elucidate the progression of auditory neural damage attributed to noise exposure.

METHODS: A retrospective cohort study was conducted through a review of the medical records for the patients who presented to a tertiary referral center. Sixty-nine participants were included in the study: 29 had noise-induced hearing loss, and 40 were healthy controls. All the participants underwent electrophysiological tests and pure-tone audiometry.

RESULTS: Nine patients showed mild hearing loss (mild hearing loss group), while the others showed worse than moderate hearing loss on puretone audiometry (severe hearing loss group). Significantly reduced wave I and V amplitudes of auditory brainstem response were present in both mild and severe hearing loss groups compared to the control group (P < .001 and P=.002, respectively), without significant differences between the mild and severe hearing loss groups. In the multivariate analysis, auditory brainstem response wave V amplitude was negatively associated with auditory brainstem response wave I-V inter-peak latency delay (B=−0.48, P=.02).

CONCLUSION: The results of the present study confirm the similarity in the electrophysiological characteristics between the mild and severe hearing loss groups. Thus, widespread disruption in the auditory neural conduction could have been established in the early period when the patient developed mild hearing loss following noise exposure.

Cite this article as: Chang Y-S, Song I, Han JH, Choi J, Chan Rah Y. Electrophysiological changes associated with the progression of noise-induced hearing loss. J Int Adv Otol. 2023;19(6):485-491.

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