The Journal of International Advanced Otology
Original Article

Evaluation of the Effects of Chronic Kidney Disease and Hemodialysis on the Inner Ear Using Multifrequency Tympanometry

1.

Department of Otorhinolaryngology, Hamanomachi Hospital, Fukuoka, Japan

2.

ISHIZU Otorhinolaryngology Clinic, Fukuoka, Japan

3.

Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

4.

Department of Otorhinolaryngology, Chidoribashi General Hospital, Fukuoka, Japan

5.

Kidney Care Unit, Kyushu University Hospital, Fukuoka, Japan

6.

Department of Integrated Therapy for Chronic Kidney Disease, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

J Int Adv Otol 2018; 14: 447-450
DOI: 10.5152/iao.2018.4736
Read: 7 Downloads: 2 Published: 03 September 2019

Abstract

 

OBJECTIVES: To evaluate the effects of chronic kidney disease (CKD) and hemodialysis (HD) on the inner ear using the G width (the width between the bimodal peaks of the conductance (G) tympanogram at 2,000 Hz), which reflects the inner ear pressure and/or the existence of endolymphatic hydrops.


MATERIALS and METHODS
: We selected five patients (10 ears) from the patients with CKD who were hospitalized for creation of arteriovenous fistula prior to initiation of HD (non-HD group), and we selected seven patients (14 ears) from the patients with CKD who were undergoing HD (the HD group). As a control group, we selected 80 healthy individuals (160 ears); these were mainly the medical staff of the hospital. We measured the G width of the control group and that of patients with CKD using multifrequency tympanometry.


RESULTS
: The mean G widths of the HD (measured just before an HD session), non-HD, and control groups were 210.7, 128.4, and 97.0 daPa, respectively. The G width of the HD group was significantly greater than that of the control and non-HD groups (p<0.01 and p<0.01, respectively; Tukey–Kramer test after one-way analysis of variance). The non-HD group also had a greater G width than the control, but it was not significant (p=0.20; Tukey–Kramer). No significant changes were observed in the G widths of the HD group, just before and after a single HD session (p=0.423; paired t-test).


CONCLUSION
: The greater G width observed in hemodialyzed CKD patients suggests either an increased inner ear pressure or the existence of endolymphatic hydrops in these patients, which is probably related to their otologic symptoms.


Cite this article as
: Tamae A, Ishizu K, Yoshida T, Kubo K, Matsumoto N, Yasui T, et al. Evaluation of the Effects of Chronic Kidney Disease and Hemodialysis on the Inner Ear Using Multifrequency Tympanometry. J Int Adv Otol 2018; 14(3): 447-50.

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ISSN1308-7649 EISSN 2148-3817