The Journal of International
Advanced Otology
Original Article

Vitamin D Insufficiency/Deficiency in Patients with Recurrent Benign Paroxysmal Positional Vertigo


Department of Oncology and Robotic Surgery, Unit of Audiology, Oncological and Robotic Head and Neck Surgery, Florence, Italy


Department of Otolaryngology, Azienda Ospedaliera Universitaria Senese, Siena, Italy


Department of Neuroscience, Psychology, Drug’s Area and Child’s Health, University of Florence, Italy


Department of Emergency Medicine, San Giuseppe Hospital, Empoli, Italy

J Int Adv Otol 2022; 18: 158-166
DOI: 10.5152/iao.2022.21269
Read: 2220 Downloads: 770 Published: 30 March 2022

BACKGROUND: The aim of this study is to verify if (1) there is a link between hypovitaminosis D and benign paroxysmal positional vertigo, (2) the number of benign paroxysmal positional vertigo relapses decreases after vitamin D supplementation; and (3) benign paroxysmal positional vertigo response to physical therapy improves after hypovitaminosis D correction.
METHODS: We enrolled 26 patients with benign paroxysmal positional vertigo and 24 subjects, who never suffered from vertigo, as a control group. All benign paroxysmal positional vertigo patients underwent physical therapy, once a week, until benign paroxysmal positional vertigo resolution. All participants were subjected to a dosage of serum 25(OH) vitamin D. In patients with hypovitaminosis D, we prescribed cholecalciferol. After 3 months of therapy, all patients were asked to undergo a second dosage of serum 25(OH) vitamin D. For each patient, we counted the number of maneuvers required to resolve each episode of benign paroxysmal positional vertigo before and after vitamin D supplementation.
RESULTS: Our results suggest that (1) there is a relationship between vitamin D deficiency and the onset of BPPV and (2) hypovitaminosis correction is able to reduce both the number of patients relapsing and the number of relapses per patient.
CONCLUSIONS: We have not found a significant effect of vitamin D supplementation as regards the responsivity of benign paroxysmal positional vertigo to physical therapy.
Cite this article as: Pecci R, Mandalà M, Marcari A, et al. Vitamin D insufficiency/deficiency in patients with recurrent benign paroxysmal positional vertigo. J Int Adv Otol. 2022;18(2):158-166.

EISSN 2148-3817