ISSN 1308-7649 | E-ISSN 2148-3817
Case Report
Repeated Attacks of Dizziness Caused by a Rare Mitochondrial Encephalomyopathy
1 Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan  
2 Department of Neurology, National Hospital Organization Saitama National Hospital, Saitama, Japan  
3 Department of Medicine, Division of Neurology, Nihon University School of Medicine, Tokyo, Japan  
4 Department of Otolaryngology, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan  
J Int Adv Otol 2018; 14: 157-160
DOI: 10.5152/iao.2018.4467
Key Words: Mitochondrial encephalomyopathy, multiple sclerosis, dizziness, eye nystamography (ENG), MRI

Cases of dizziness caused by multiple sclerosis are commonly reported, but those caused by mitochondrial encephalomyopathy have been rarely reported. Particularly, the description of eye nystagmography (ENG) using caloric and optokinetic nystagmus tests has not been reported to date. We encountered the case of a 40-year-old woman with mitochondrial encephalomyopathy who visited us with the chief complaint of dizziness. At first, we considered multiple sclerosis based on the magnetic resonance imaging (MRI) findings and dizziness. Repeated attacks of dizziness and serum lactic acid levels suggested mitochondrial encephalomyopathy. A muscle biopsy confirmed the diagnosis. ENG findings suggested central vestibular disorder of the cerebellum and brainstem. This case suggests that we should not rule out the differential diagnosis of a very rare mitochondrial encephalomyopathy in patients who experience dizziness with MRI findings indicative of multiple sclerosis.


Cite this article as: Toi T, Nomura Y, Kishino A, Shigihara S, Oshima T, Ishikawa H, et al. Repeated Attacks of Dizziness Caused bya Rare Mitochondrial Encephalomyopathy. J Int Adv Otol 2018; 14(1): 157-60.

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